Pathology Terminology

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Medical

14th February 2009

Ravi Patel

USA

84

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Adenocarcinoma

A carcinoma characterized by glandular architecture and/or secretary differentiation

Adenoma

A benign epithelial neoplasm usually showing glandular architecture. In some cases, can be considered precancerous

AMACR

Α-methylacyl-CoA racemase, an enzyme over expressed in some prostatic neoplasia that can be targeted with antibody staining

Anaplasia

The condition of being poorly differentiated or lacking differentiation • common characteristic of malignant cells • often with marked or variable nuclear enlargement.

Anticoagulant

Inhibits fibrin clotting

Antithrombic

Inhibits platelet plugging

Apoptosis

An active, highly regulated, ATP-dependent process of cellular self-destruction that involves individual cells. • Can be pathologic • Important to development

Atherosclerosis

A general term for diseases associated with "hardening" or thickening of the walls of arteries

Atrophy

A decrease in tissue mass resulting from a decrease in cell number, cell size, or both

BPH

Benign prostatic hyperplasia. Can cause elevated PSA as well as a positive digital rectal exam finding. May impinge urethra, causing symptoms similar to prostate cancer

Carcinoma

A malignant neoplasm of epithelial origin. Characterized by invasion or metastasis

Carcinoma in situ

A pre-malignant condition that has the cytological features of malignancy but is confined to the epithelium. Must have full-thickness cytological atypia and can be considered the end-point of severe dysplasia

Cardiogenic shock

Shock resulting from acute severe failure of myocardial muscle function